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NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176 | PNAS
Catalytic subunits of the phosphatase calcineurin interact with NF-κB-inducing kinase (NIK) and attenuate NIK-dependent gene expression | Scientific Reports
Anti-Nik related kinase Antibody Products | Biocompare
IJMS | Free Full-Text | Targeting NF-κB-Inducing Kinase (NIK) in Immunity, Inflammation, and Cancer
Non-canonical NF-κB signaling pathway | Cell Research
Functional interplay between NF-κB-inducing kinase and c-Abl kinases limits response to Aurora inhibitors in multiple myeloma | Haematologica
NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus | Nature Communications
Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) | Journal of Medicinal Chemistry
Functional interplay between NF-κB-inducing kinase and c-Abl kinases limits response to Aurora inhibitors in multiple myeloma | Haematologica
NHRI researchers report expression of Nik-related kinase in smooth muscle cells attenuates vascular inflammation and intimal hyperplasia – NHRI Communications
The discovery of quinoline derivatives, as NF-κB inducing kinase (NIK) inhibitors with anti-inflammatory effects in vitro, low toxicities against T cell growth - ScienceDirect
Nik‐related kinase is targeted for proteasomal degradation by the chaperone‐dependent ubiquitin ligase CHIP - Naito - 2020 - FEBS Letters - Wiley Online Library
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
NIK as a Druggable Mediator of Tissue Injury: Trends in Molecular Medicine
Frontiers | NF-κB Inducing Kinase Regulates Intestinal Immunity and Homeostasis
IJMS | Free Full-Text | Targeting NF-κB-Inducing Kinase (NIK) in Immunity, Inflammation, and Cancer
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing)
Expression of Nik-related kinase in smooth muscle cells attenuates vascular inflammation and intimal hyperplasia - Figure f3 | Aging
Frontiers | The Therapeutic Potential of Targeting NIK in B Cell Malignancies
Controlling the Fate of NIK: A Central Stage in Noncanonical NF-κB Signaling | Science Signaling
Cells | Free Full-Text | Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets
Cells | Free Full-Text | Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets
The non-canonical NF-κB pathway in immunity and inflammation | Nature Reviews Immunology
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A